UCI's Daniele Piomelli is one of the world's leading researchers on endocannabinoids. He discovered that eating fatty foods like potato chips and french fries triggers the production of these naural chemicals that make you want to eat more -- lots more. This craving was a useful signal when ancient humans had rare opportunities to find fat for their diets. Today, it is a factor in the obesity epidemic. Dr. Piomelli's research is leading to new treatments for anxiety, depression, and obesity.